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MUTANT LINE   NMF333 Contact JAX-NMF for ordering information
Synopsis:

The mutants show head tilt and occasional head tossing behavior.

Detailed Phenotype Description:

These mutants were detected through routine inspections for overt abnormal behavior; head- and body tilt can be observed at approximately 4 weeks of age (average onset 4.6 +/- 0.6 weeks; n=15). Male or female mutants have been produced and the colony is maintained through regular breeding. Standard pathology work-up and a whole-mount ear exam on one mutant (56 days of age) revealed no abnormalities.

View video

Abnormal Assays:Domain(s):
Overt movement/posture (view protocol) Auditory/Vestibular, Visible Mutants


MUTANT LINE INFORMATION
Mutant Line Name
NMF333 (view more detail at Mutagenesis Center)
Gene Symbol nmf333 (view more info on gene)
Gene Name neuroscience mutagenesis facility333
Allele Symbol nmf333
Allele Name neuroscience mutagenesis facility333
MGI ID MGI:3526726 (view MGI record)
Originating Mutagenesis Center The Jackson Laboratory (contact for ordering information)
Mutation Type chemically induced mutation (CI)
Strain Designation A.B6 Tyr+-nmf333/J
Video view video


HERITABILITY AND MAPPING INFORMATION
Background Strain A.B6 Tyr+
Mode of Inheritance Recessive
Heritability Proven
Chromosome Location 8
Mapping Interval D8Mit248 - 5 cM (LOD 4.0) - D8Mit213 - 10 cM (LOD 3.2) - [D8Mit13, NMF333] 0 cM (LOD 6.0)
Identified Mutation
Map
(Click the image to zoom in.)
Image courtesy of MGI


STATUS INFORMATION
Availability
  • Live mice (LM)
Confirmation Date 24-Mar-2005
Availability Date 05-Apr-2005
Off-Shelf Date
Line History Comments (22) NMF333/DNA have been requested by and distributed to 3 investigators.