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| MUTANT LINE 112TNR |
Contact TMGC for ordering information
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| Synopsis: |
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Exceptional perfomance on rotarod training and performance |
| Detailed Phenotype Description: |
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This recessive mutation (tmgc56), linked to Chr 15, was detected in the progeny of C57BL/6JRn males given one dose of 150 mg/kg ENU. The 112TNR pedigree is highly adept at staying on the rotarod. The first measure is rota train time (which is seconds that the mouse remains on the rotarod [ROTA_TRAIN_TIME). The mean (+/- SD) for the TNR's as a whole is 42+/-6.6 while that for 112TNR is 84.8 +/- 16.6. This makes this pedigree 6.5 SD away from the mean. The next nearest pedigree has a mean of 65.7 sec. Because of the high baseline ability, these mice also are adept at remaining on the rotarod after ethanol with a mean of 58.7 +/- 17.5 while that for all the TNRs is 28.8 +/- 4.4 [ROTA_ETHA_TIME]. Again, this pedigree is over 6 SD from the mean.
Detailed data sheet
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| Abnormal Assays: | Domain(s): |
| Rotarod performance (view protocol) |
Alcohol Abuse
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MUTANT LINE INFORMATION |
Mutant Line Name
| 112TNR (view more detail at Mutagenesis Center) |
| Gene Symbol |
tmgc56
(view more info on gene)
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| Gene Name |
Tennessee Mouse Genome Consortium 56 |
| Allele Symbol |
tmgc56 |
| Allele Name |
Tennessee Mouse Genome Consortium 56 |
| MGI ID |
MGI:3589256 (view MGI record) |
| Originating Mutagenesis Center |
Tennessee Mouse Genome Consortium (contact for ordering information) |
| Mutation Type |
chemically induced mutation (CI)
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| Strain Designation |
STOCK 112TNR |
| Data Sheet |
view data sheet |
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HERITABILITY AND MAPPING INFORMATION |
| Background Strain |
Mixed, noninbred |
| Mode of Inheritance |
Recessive |
| Heritability |
Proven (Segregation In Progress, view detail) |
| Chromosome Location |
15 |
| Mapping Interval |
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| Identified Mutation |
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STATUS INFORMATION |
| Availability |
- Live mice (LM)
- Cryopreserved sperm (SP)
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| Confirmation Date |
14-Sep-2005 |
| Availability Date |
23-Sep-2005 |
| Off-Shelf Date |
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| Line History Comments |
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