search mouse lines by keyword   advanced search



RETURN TO MOUSE LINE SEARCH



HOME    ABOUT NEUROMICE    NEWS    MOUSE LINES    ASSAYS    FAQ    CONTACT    FEEDBACK

MUTANT LINE   223CH19 Contact TMGC for ordering information
Synopsis:

Decreased anxiety related behavior in light/dark task.

Detailed Phenotype Description:

This autosomal recessive mutation (tmgc58), linked to Chr. 19, was detected in the progeny of C57BL/6-19PWK males given one dose of 150 mg/kg ENU. 223CH19 shows decreased anxiety in the light/dark task. To date we have tested 12 animals representing at least 3 generations. The mean for the pedigree is 3.13 standard deviations above the population mean.

Detailed data sheet

Abnormal Assays:Domain(s):
Light/Dark exploration (view protocol) Emotional Behavior


MUTANT LINE INFORMATION
Mutant Line Name
223CH19 (view more detail at Mutagenesis Center)
Gene Symbol tmgc58 (view more info on gene)
Gene Name Tennessee Mouse Genome Consortium 58
Allele Symbol tmgc58
Allele Name Tennessee Mouse Genome Consortium 58
MGI ID MGI:3589258 (view MGI record)
Originating Mutagenesis Center Tennessee Mouse Genome Consortium (contact for ordering information)
Mutation Type chemically induced mutation (CI)
Strain Designation C57BL/6-19PWK-tmgc58
Data Sheet view data sheet


HERITABILITY AND MAPPING INFORMATION
Background Strain C57BL/6-19PWK
Mode of Inheritance Recessive
Heritability Proven (Segregation In Progress, view detail)
Chromosome Location 19
Mapping Interval
Identified Mutation


STATUS INFORMATION
Availability
  • Live mice (LM)
  • Cryopreserved sperm (SP)
Confirmation Date 14-Jan-2005
Availability Date 23-Sep-2005
Off-Shelf Date
Line History Comments